50/50

Director Jonathan Levine's 50/50 casts Joseph Gordon-Levitt as a young man afflicted with a rare form of spinal cancer, and Seth Rogen as his loud, loutish, perpetually stoned best friend. Consequently, I expected the film's title and my chances of actually enjoying the movie to be one and the same. It's always great seeing Gordon-Levitt onscreen, but is there anyone left who isn't longing for a break from Rogen's braying, one-note shtick, even if, as he is here, the man isn't just presumably but damn near literally playing himself? (50/50's script is loosely autobiographical, and Rogen and author Will Reiser are real-life pals and frequent writing partners.)